Response to Spironolactone in Resistant Hypertension
نویسندگان
چکیده
منابع مشابه
Spironolactone in resistant hypertension.
Spironolactone in Resistant Hypertension To the Editor: The recent article by Chapman1 and the accompanying editorial by Goodfriend2 provide an evidence base for an increased use of spironolactone in patients with resistant hypertension. The usual definition of resistant hypertension states that a diuretic should have been included in the regimen of 3 or more drugs. In this Anglo-Scandinavian C...
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2032 www.thelancet.com Vol 386 November 21, 2015 Resistant hypertension is characterised by failure to achieve a blood pressure of less than 140/90 mm Hg while on maximum tolerated doses of three diff erent classes of antihypertensive drugs, including a diuretic appropriate for kidney function. While often ascribed to medication non-adherence, true resistant cases of hypertension are linked to ...
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This study was designed to assess the effect of the addition of low-dose spironolactone on blood pressure (BP) in patients with resistant arterial hypertension. Patients with office systolic blood pressure (SBP) >140 mm Hg or diastolic blood pressure (DBP)>90 mm Hg despite treatment with at least 3 antihypertensive drugs, including a diuretic, were enrolled in this double-blind, placebo-control...
متن کاملEfficacy of spironolactone therapy in patients with true resistant hypertension.
The role of spironolactone in resistant hypertension management is unclear. The aim of this prospective trial was to evaluate the antihypertensive effect of spironolactone in patients with true resistant hypertension diagnosed by ambulatory blood pressure monitoring. A total of 175 patients had clinical and complementary exams obtained at baseline and received spironolactone in doses of 25 to 1...
متن کاملSpironolactone and doxazosin treatment in patients with resistant hypertension.
INTRODUCTION AND OBJECTIVES The aim of this study was to evaluate the use of spironolactone and doxazosin as treatment for patients with resistant hypertension. METHODS This retrospective study involved 181 outpatients with resistant hypertension (defined as a failure of blood pressure [BP] control despite treatment with three drugs, one of which was a diuretic) who received additional spiron...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2007
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.107.093070